A plain vanilla, stockinette sock is working much better than a fancy stitch pattern did with this yarn. I honestly can't explain why the pooling pattern changed partway down the leg (the number of stitches stayed the same, as did my needles and my tension), but I think it would look even weirder with the slipped stitches of Twisted. Also, I'm super curious what the pooling pattern will be on the second sock!
On an only mildly related topic
, I have a skein of sock yarn in my stash that will work perfectly for Twisted, and after starting it and frogging it twice, I really feels like it deserves a chance to get knitted next.